Low Plasma β-Endorphin in Post-Traumatic Stress Disorder-Reference-Cited by-同舟云学术

Low Plasma β-Endorphin in Post-Traumatic Stress Disorder

Published:1989-06 Issue:2 Volume:23 Page:269-273
ISSN:0004-8674
Container-title:Australian & New Zealand Journal of Psychiatry
language:en
Short-container-title:Aust N Z J Psychiatry

Author:

Hoffman Linda¹,Watson Paddy Burges¹,Wilson George²,Montgomery Joan³

Affiliation:

1. Repatriation General Hospital, Hobart, Tasmania

2. Dept. of Psychology, University of Tasmania, Hobart, Tasmania

3. Vietnam Veterans' Counselling Service, Hobart

Abstract

We compared serum cortisol, ACTH and plasma P-endorphin in 21 Post-Traumatic Stress Disorder patients and 20 controls. Although we found no important disturbance in diurnal rhythms, the PTSD patients had significantly higher A.M. serum cortisols compared with controls. Both A.M. and P.M. plasma P-endorphins in PTSD patients were significantly lower compared with controls. These data suggest that plasma P-endorphin may be a marker for PTSD and that chronic endogenous opioid depletion may play a role in the pathogenesis and perpetuation of this disorder.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.3109/00048678909062145

Reference19 articles.

1. A psychophysiological study of Post Traumatic Stress Disorder in Vietnam veterans

2. Validation of a multimethod assessment of posttraumatic stress disorders in Vietnam veterans.

Cited by 54 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. CpG Methylation Levels in HPA Axis Genes Predict Chronic Pain Outcomes Following Trauma Exposure;The Journal of Pain;2023-07

2. Emotional numbing in PTSD is associated with lower amygdala reactivity to pain;Neuropsychopharmacology;2022-08-09

3. Can the migration process influence the clinical expression of heroin use disorder in migrants to Italy?;CNS Spectrums;2020-01-23

4. The failing cascade: Comorbid post traumatic stress- and opioid use disorders;Neuroscience & Biobehavioral Reviews;2019-08

5. The opioid system in stress-induced memory disorders: From basic mechanisms to clinical implications in post-traumatic stress disorder and Alzheimer's disease;Progress in Neuro-Psychopharmacology and Biological Psychiatry;2019-01