Physicochemical property profile for brain permeability: comparative study by different approaches-Reference-Cited by-同舟云学术

Physicochemical property profile for brain permeability: comparative study by different approaches

Published:2016-02-06 Issue:7 Volume:24 Page:655-662
ISSN:1061-186X
Container-title:Journal of Drug Targeting
language:en
Short-container-title:Journal of Drug Targeting

Author:

Raevsky Oleg A.¹,Grigorev Veniamin Y.¹,Polianczyk Daniel E.¹,Sandakov German I.¹,Solodova Svetlana L.¹,Yarkov Alexander V.¹,Bachurin Sergey O.²,Dearden John C.³

Affiliation:

1. Department of Computer-Aided Molecular Design, Institute of Physiologically Active Compounds, Russian Academy of Science, Chernogolovka, Russia;

2. Department of Biomedicinal Chemistry, Institute of Physiologically Active Compounds, Russian Academy of Science, Chernogolovka, Russia;

3. School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK

Publisher

Informa UK Limited

Subject

Pharmaceutical Science

Link

https://www.tandfonline.com/doi/pdf/10.3109/1061186X.2015.1132224

Reference42 articles.

1. CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure

2. Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists

3. Estimation of Caco-2 Cell Permeability using Calculated Molecular Descriptors

4. Estimation of Blood-Brain Barrier Crossing of Drugs Using Molecular Size and Shape, and H-Bonding Descriptors

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