A comparative molecular dynamics study on BACE1 and BACE2 flap flexibility
Author:
Affiliation:
1. Molecular Modelling & Drug Design Research Group, School of Health Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa
Publisher
Informa UK Limited
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://www.tandfonline.com/doi/pdf/10.3109/10799893.2015.1130058
Reference44 articles.
1. Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer?s disease �-secretase (BACE-1)
2. Amyloid β secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease
3. Inhibitors of Alzheimer’s BACE-1 with 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structure
4. A necrodane monoterpenoid fromLavandula luisieriessential oil as a cell-permeable inhibitor of BACE-1, theβ-secretase in Alzheimer's disease
5. Transmembrane Amyloid-Related Proteins in CSF as Potential Biomarkers for Alzheimer’s Disease
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