The One-Electron Reduction Potential of 3-Amino-1, 2, 4-benzotriazine 1, 4-dioxide (Tirapazamine): A Hypoxia-Selective Bioreductive Drug
Author:
Publisher
Informa UK Limited
Subject
General Medicine,Biochemistry
Link
http://www.tandfonline.com/doi/pdf/10.3109/10715769609149061
Reference21 articles.
1. SR-4233: A new bioreductive agent with high selective toxicity for hypoxic mammalian cells
2. Molecular mechanisms for the hypoxiadependent activation of 3-amino-1,2,4-benzotriazine-1, 4-dioxide (SR 4233)
3. SR 4233 (Tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours
4. Structure-activity relationships for benzotriazine DI-N-oxides
5. Bioreductive drugs for cancer therapy: The search for tumor specificity
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