Synthesis and biological evaluation of 2,5-disubstituted 1,3,4-oxadiazole derivatives with both COX and LOX inhibitory activity-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of 2,5-disubstituted 1,3,4-oxadiazole derivatives with both COX and LOX inhibitory activity

Published:2011-02-11 Issue:6 Volume:26 Page:767-776
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Akhter Mymoona¹,Akhter Nayeema²,Alam M. M.¹,Zaman M. S.¹,Saha Rikta¹,Kumar A.³

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard University, New Delhi, India

2. Chemistry Division, Indian Institute of Integrated Medicine, CSIR, Srinagar, Kashmir

3. Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, TX, USA

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.3109/14756366.2010.550890

Reference51 articles.

1. Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy? 1 1Abbreviations: NSAIDs, nonsteroidal anti-inflammatory drugs; COX, cyclooxygenase; LT, leukotriene; 5-LOX, 5-lipoxygenase; PG, prostaglandin; DFU, 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsuphonyl)-phenyl-2(5H)-furanone; and DFP, diisopropyl fluorophosphate.

2. Prostaglandin endoperoxide synthase: structure and catalysis

3. Cyclooxygenase inhibitors – current status and future prospects

4. Celecoxib, a selective cyclooxygenase-2 inhibitor for the treatment of rheumatoid arthritis and osteoarthritis

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2. Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective;ACS Omega;2023-05-09

3. Parsing p-tolyloxy-1,3,4-oxadiazolepropanamides as 15-lipoxygenase inhibitors prop up by in vitro and in silico profiling including structure determination;Journal of Molecular Structure;2023-03

4. Recent chemistry and applications of 1,3,4-oxadiazoles;Advances in Heterocyclic Chemistry;2023

5. Assessing p-tolyloxy-1,3,4-oxadiazole acetamides as lipoxygenase inhibitors assisted by in vitro and in silico studies;Bioorganic Chemistry;2022-12

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