Microwave-assisted synthesis of sec/tert-butyl 2-arylbenzimidazoles and their unexpected antiproliferative activity towards ER negative breast cancer cells

Author:

Abdul Rahim Aisyah Saad12,Muhamad Salhimi Salizawati12,Arumugam Natarajan12,Chung Pin Lim12,Shy Yee Ng12,Muttiah Nithya Niranjini12,Boon Keat Wong12,Abd. Hamid Shafida23,Osman Hasnah24,Mat Ishak b.24

Affiliation:

1. School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia

2. Kulliyyah of Science, International Islamic University Malaysia, Jalan Istana, Bandar Indera Mahkota, Kuantan, Malaysia

3. School of Chemical Sciences, Universiti Sains Malaysia, Penang, Malaysia

4. Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bandar Putra Bertam, Penang, Malaysia

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Reference38 articles.

1. World Health Organisation - Breast Cancer: Prevention and Control. Available at http://www.who.int/ cancer/detection/breastcancer/en/. Accessed 23 June 2012.

2. The New Era in Cancer Research

3. Rosen ST. Cancer chemoprevention. Bergan RC, ed. New York: Academic Publisher; 2001:137–154.

4. Chemoprevention of breast cancer with selective oestrogen-receptor modulators

5. Molecular and pharmacological aspects of antiestrogen resistance

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