Convergent QSAR studies on a series of NK3 receptor antagonists for schizophrenia treatment

Author:

Primi Marina Candido1,Maltarollo Vinícius Gonçalves1,Magalhães Juliana Gallottini1,Malta de Sá Matheus2,Rangel-Yagui Carlota Oliveira3,Trossini Gustavo Henrique Goulart1

Affiliation:

1. Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, SP, Brazil,

2. Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, SP, Brazil, and

3. Department of Biochemical and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of São Paulo, SP, Brazil

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Reference43 articles.

1. WHO, World Health Organization. Mental Health: schizophrenia. Available from: http://www.who.int/mental_health/management/schizophrenia/en/ [last accessed 13 Jun 2013]

2. NK3 receptor antagonists: the next generation of antipsychotics?

3. Identification of a new series of non-peptidic NK3 receptor antagonists

4. Discovery of 3-aryl-5-acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor

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