Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2

Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2–P4 study

Published:2015-03-20 Issue:2 Volume:31 Page:332-339
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Ang Melgious J. Y.¹,Lau Qiu Ying¹,Ng Fui Mee¹,Then Siew Wen¹,Poulsen Anders¹,Cheong Yuen Kuen¹,Ngoh Zi Xian¹,Tan Yong Wah²,Peng Jianhe¹,Keller Thomas H.¹,Hill Jeffrey¹,Chu Justin J. H.²³,Brian Chia C. S.¹

Affiliation:

1. Experimental Therapeutics Centre, Agency for Science, Technology and Research (A*STAR), Singapore,

2. Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, and

3. Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology, National University of Singapore, Singapore

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.3109/14756366.2015.1018245

Reference21 articles.

1. Host and virus determinants of picornavirus pathogenesis and tropism

2. Developments towards antiviral therapies against enterovirus 71

3. An overview of the evolution of enterovirus 71 and its clinical and public health significance

4. Enterovirus infections of the central nervous system

5. Enterovirus 71 Outbreak in the People's Republic of China in 2008

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