Self-reported Side Effects in children and Adolescents Taking Risperidone

Author:

Byrne Simon1,Walter Garry2,Hunt Glenn3,Soh Nerissa4,Cleary Michelle5,Duffy Paul6,Crawford Geoff7,Krabman Peter8,Concannon Patrick9,Malhi Gin10

Affiliation:

1. Research Assistant, Northern Sydney Central Coast Health, NSW, Australia

2. Professor of Child and Adolescent Psychiatry, Discipline of Psychological Medicine, University of Sydney, and Area Clinical Director, Child and Adolescent Mental Health Services, Northern Sydney Central Coast Health, NSW, Australia

3. Senior Research Fellow, Discipline of Psychological Medicine, University of Sydney and Research Unit, Sydney South West Area Mental Health Service, NSW, Australia

4. Research Officer, Child and Adolescent Mental Health Services, Northern Sydney Central Coast Health, NSW, Australia

5. Clinical Nurse Consultant, Research Unit, Sydney South West Area Mental Health Service, NSW, Australia

6. Pediatrician in private practice, Dee Why, NSW, Australia

7. Pediatrician in private practice, Sydney, NSW, Australia

8. Medical Director, Coral Tree Family Service, Northern Sydney Central Coast Health, NSW, Australia child psychiatrist in private practice, Eastwood, NSW, Australia

9. Pediatrician in private practice, Chatswood, NSW, Australia

10. Head, Academic Discipline of Psychological Medicine, Northern Clinical School, University of Sydney, Sydney, NSW, Australia

Abstract

Objective: We aimed to describe medication side effects in a cross-section of young people taking low-dose risperidone, using a self-report measure. Methods: The Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS) was completed by 66 patients aged between 6 and 18 years who had been taking low-dose risperidone (alone or in conjunction with other medications) for up to 13 years. Results: Young persons, overall, seemed to tolerate risperidone well, but longer exposure to the medication was associated with higher side effect levels, particularly for the psychic (pertaining to mind and emotion) and extrapyramidal subscales. The most common complaints related to psychic side effects, such as tiredness, difficulty concentrating, difficulty remembering things and increased dreaming. Conclusions: Clinicians need to monitor the side effects of young patients taking low doses of risperidone, and other psychotropics, and maintain vigilance in those who have been taking medication for extended periods.

Publisher

SAGE Publications

Subject

Psychiatry and Mental health

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Assessing and Reporting the Adverse Effects of Antipsychotic Medication;Clinical Neuropharmacology;2016-01

2. Health Conditions, Learning, and Behavior;Evidence-Based Practices in Behavioral Health;2016

3. Experience of psychotropic drug use among young people with mental health problems;Nordic Journal of Nursing Research;2015-07-09

4. Consenso del GEITDAH sobre los trastornos de conducta en niños y adolescentes;Revista de Neurología;2015

5. Antipsychotic drugs;A worldwide yearly survey of new data in adverse drug reactions and interactions;2012

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