1. Department of Biomedical Pharmaceutics, Laboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan
2. Bioresponses and Regulation, Field of Biofunctional Control, Medical Information Sciences Division, United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University,1-1 Yanagido, Gifu 501-1193, Japan