1. , Abbreviations used: IgE, immunoglobulin E; RBL, rat basophilic leukemia; ϵ R, IgE-binding component; SDS-PAGE, polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate; DMS, dimethyl suberimidate dihydrochloride; DTBP, dimethyl 3,3′-dithiobispropioni-midate dihydrochloride; BBS, borate-buffered saline; PBS, phosphate-buffered saline; MW, molecular weight; SG, stacking gel, D, tracking dye; XϵR, polypeptide which crosslink's to ϵR
2. Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation.
3. Fewtrell C., Metzger H. 1979, Unpublished results
4. A new concept of triggering mechanisms of IgE-mediated histamine release