Identification of Cyclobenzaprine-10, 11-Epoxide and other Metabolites after Incubation of Cyclobenzaprine with Rat Liver Microsomes
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.3109/00498257509060377
Reference5 articles.
1. Mass spectrometric identification of anN-oxide formed by incubation ofN,N-dimethyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine with rat liver microsomes
2. Mass Spectrometric Characterization of Carbamazepine-10,11-epoxide,a Carbamazepine Metabolite Isolated from Human Urine
3. Hepatic mixed function oxidase activity in rapidly prepared microsomes
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1. Study of degradation mechanisms of cyclobenzaprine by LC-MS/MS;Anal. Methods;2014
2. Cyclobenzaprine;Handbook of Metabolic Pathways of Xenobiotics;2013-10-13
3. Product enantioselectivity in the microsomal epoxide hydrolase catalyzed hydrolysis of 10,11-dihydro-10,11-epoxy-5H-dibenzo[a,d]cycloheptene;The Journal of Organic Chemistry;1989-02
4. The low reactivity of 5H-dibenzo[a, cflcycloheptene 10,ll-oxide in microsomal epoxide hydrolase catalysed hydration;Xenobiotica;1989-01
5. Cyclobenzaprine Hydrochloride;Analytical Profiles of Drug Substances;1988
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