Identification of polymorphisms in the 3′-untranslated region of the human pregnane X receptor (PXR) gene associated with variability in cytochrome P450 3A (CYP3A) metabolism-Reference-Cited by-同舟云学术

Identification of polymorphisms in the 3′-untranslated region of the human pregnane X receptor (PXR) gene associated with variability in cytochrome P450 3A (CYP3A) metabolism

Published:2010-01-18 Issue:2 Volume:40 Page:146-162
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Oleson L.,von Moltke L. L.,Greenblatt D. J.,Court M. H.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498250903420243

Reference36 articles.

1. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

2. SXR, a novel steroid and xenobioticsensing nuclear receptor

3. Screening for polymorphisms in the PXR gene in a Dutch population

4. A predicted functional single-nucleotide polymorphism of bone morphogenetic protein-4 gene affects mRNA expression and shows a significant association with cutaneous melanoma in Southern Italian population

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