Determination of P4501A2 activity in human liver microsomes using [3-14C-methyl]caffeine
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.3109/00498259509046663
Reference20 articles.
1. Comparison of Caffeine Metabolism by Slices, Microsomes and Hepatocyte Cultures from Adult Human Liver
2. Fluvoxamine is a potent inhibitor of cytochrome P4501A2
3. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450
4. Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.
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