Metabolism of benzbromarone in man: structures of new oxidative metabolites, 6-hydroxy- and 1″-oxo-benzbromarone, and the enantioselective formation and elimination of 1″-hydroxybenzbromarone-Reference-Cited by-同舟云学术

Metabolism of benzbromarone in man: structures of new oxidative metabolites, 6-hydroxy- and 1″-oxo-benzbromarone, and the enantioselective formation and elimination of 1″-hydroxybenzbromarone

Published:1993-01 Issue:12 Volume:23 Page:1435-1450
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

De Vries J. X.,Walter-Sack I.,Voss A.,Forster W.,Ilisistegui Pons P.,Stoetzer F.,Spraul M.,Ackermann M.,Moyna G.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498259309059452

Reference25 articles.

1. Liquid chromatography-mass spectrometry in metabolic research

2. Metabolism of benzbromarone in man

3. Polymer supported reagents. Chromic acid on anion exchange resins. A simple and practical oxidation of alcohols to aldehydes and ketones

4. Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism) — Increased michaelis constant (km) and loss of stereoselectivity of bufuralol 1′-hydroxylation in poor metabolizers

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