The Dangers of Dextropropoxyphene

Abstract

Objective: Dextropropoxyphene is a commonly used analgesic despite its high toxicity in overdose and potential for abuse and dependence. This case report highlights these dangers. Clinical picture: The case of a female who was addicted to dextropropoxyphene as an alternative to other opioids is described. Its use in high doses with other psychotropic agents resulted in adverse health effects. Treatment: The patient was treated with methadone and psychosocial interventions. Outcome: The patient reduced her drug use and experienced improved physical health and psychosocial functioning. Conclusions: Caution is needed when prescribing dextropropoxyphene because of its adverse effects compared with equally efficacious analgesics.