Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms-Reference-Cited by-同舟云学术

Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms

Published:2011-10-12 Issue:1 Volume:42 Page:57-74
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Harrison Anthony,Gardner Iain,Hay Tanya,Dickins Maurice,Beaumont Kevin,Phipps Alex,Purkins Lynn,Allan Gill,Christian Rachelle,Duckworth Jonathan,Gurrell Ian,Kempshall Sarah,Savage Mark,Seymour Mark,Simpson Marie,Taylor Louise,Turnpenny Paul

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498254.2011.622418

Reference56 articles.

1. Assessment of the absorption, metabolism and absolute bioavailability of maraviroc in healthy male subjects

2. Predictability of intranasal pharmacokinetics in man using pre-clinical pharmacokinetic data with a dopamine 3 receptor agonist, PF-219061

3. EVALUATION OF MICRODOSING TO ASSESS PHARMACOKINETIC LINEARITY IN RATS USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY

4. Volume of Distribution at Steady State for a Linear Pharmacokinetic System with Peripheral Elimination

5. American College of Clinical Pharmacology Position Statement on the Use of Microdosing in the Drug Development Process

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