The multiple-dosing pharmacokinetics of artemether, artesunate, and their metabolite dihydroartemisinin in rats
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.3109/00498254.2010.542257
Reference25 articles.
1. Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects
2. Antimalarial Artemisinin Drugs Induce Cytochrome P450 and MDR1 Expression by Activation of Xenosensors Pregnane X Receptor and Constitutive Androstane Receptor
3. Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration
4. Pharmacokinetics of a Five-day Oral Dihydroartemisinin Monotherapy Regimen in Patients with Uncomplicated Falciparum Malaria
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