A simplified approach to predict CYP3A-mediated drug–drug interactions at early drug discovery: validation with clinical data-Reference-Cited by-同舟云学术

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A simplified approach to predict CYP3A-mediated drug–drug interactions at early drug discovery: validation with clinical data

Published:2012-12-17 Issue:7 Volume:43 Page:592-597
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Rioux Nathalie,Batonga Joëlle,Colombo Federico,Massé Jonathan,Zouki Christine,Ribadeneira Maria D.,Duan Jianmin,Bethell Richard C.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498254.2012.751141

Reference29 articles.

1. Dose of midazolam should be reduced during diltiazem and verapamil treatments.

2. THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

3. Comparative Use of Isolated Hepatocytes and Hepatic Microsomes for Cytochrome P450 Inhibition Studies: Transporter-Enzyme Interplay

4. Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: Comparison with ritonavir

5. The Liver Partition Coefficient-Corrected Inhibitory Quotient and the Pharmacokinetic-Pharmacodynamic Relationship of Directly Acting Anti-Hepatitis C Virus Agents in Humans

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Risk assessment of drug–drug interactions using hepatocytes suspended in serum during the drug discovery process;Xenobiotica;2013-09-27

2. Assessment of CYP3A-mediated drug-drug interaction potential for victim drugs using anin vivorat model;Biopharmaceutics & Drug Disposition;2013-08

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