Population pharmacokinetic modelling and simulation of 5-fluorouracil incorporating a circadian rhythm in rats
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.3109/00498254.2015.1100767
Reference37 articles.
1. Circadian rhythm of 5-fluorouracil population pharmacokinetics in patients with metastatic colorectal cancer
2. LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients
3. Individual Fluorouracil Dose Adjustment in FOLFOX Based on Pharmacokinetic Follow-Up Compared With Conventional Body-Area-Surface Dosing: A Phase II, Proof-of-Concept Study
4. Circadian variation in plasma 5-fluorouracil concentrations during a 24 hour constant-rate infusion
5. Hepatic extraction ratio of 5-fluorouracil in rats
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