The metabolism of 4-bromoaniline in the bile-cannulated rat: application of ICPMS (79/81Br), HPLC-ICPMS & HPLC-oaTOFMS
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.3109/00498254.2015.1007491
Reference21 articles.
1. High-performance liquid chromatography-UV diode array, inductively coupled plasma mass spectrometry (ICMPS) and orthogonal acceleration time-of-flight mass spectrometry (oa-TOFMS) applied to the simultaneous detection and identification of metabolites of 4-bromoaniline in rat urine
2. Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry
3. Directly coupled liquid chromatography with inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry for the identification of drug metabolites in urine: application to diclofenac using chlorine and sulfur detection
4. Use of the bromine isotope ratio in HPLC-ICP-MS and HPLC-ESI-MS analysis of a new drug in development
5. Metabolism of 3-chloro-4-fluoroaniline in rat using [14C]-radiolabelling,19F-NMR spectroscopy, HPLC-MS/MS, HPLC-ICPMS and HPLC-NMR
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1. A fast and automated separation and quantification method for bromine speciation analyzing bromide and 5-bromo-2’-deoxyuridine in enzymatically digested DNA samples via ion chromatography-inductively coupled plasma-mass spectrometry;Journal of Chromatography A;2021-08
2. Strategies for metabolite profiling based on liquid chromatography;Journal of Chromatography B;2017-02
3. UNDERSTANDING DRUG METABOLISM IN HUMANS;Metabolite Safety in Drug Development;2016-07-11
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