Systematic review of the effect of intravenous lipid emulsion therapy for local anesthetic toxicity

Author:

Hoegberg Lotte C. G.1,Bania Theodore C.2,Lavergne Valéry3,Bailey Benoit45,Turgeon Alexis F.6,Thomas Simon H. L.7,Morris Martin8,Miller-Nesbitt Andrea8,Mégarbane Bruno9,Magder Sheldon10,Gosselin Sophie511,

Affiliation:

1. Department of Anesthesiology, Danish Poisons Information Centre, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark;

2. Department of Emergency Medicine, Mt Sinai Roosevelt, Mt Sinai St. Luke's, Icahn School of Medicine, New York, NY, USA;

3. Department of Medical Biology, Sacré-Coeur Hospital, University Of Montréal, Montréal, Canada;

4. Division of Emergency Medicine, Department of Pediatrics, CHU Sainte-Justine, Montreal, Canada;

5. Centre Antipoison du Québec, Québec, Canada;

6. Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, CHU de Québec – Université Laval Research Center, Population Health and Optimal Health Practices Unit, Université Laval, Québec City, Canada;

7. National Poisons Information Service (Newcastle) and Medical Toxicology Centre, Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom;

8. Schulich Library of Science and Engineering, McGill University, Montréal, Canada;

9. Department of Medical and Toxicological Intensive Care, Lariboisière Hospital, Paris-Diderot University, Paris, France;

10. Department of Critical Care, McGill University Health Centre, Montreal, Canada;

11. Department of Emergency Medicine, McGill University Health Centre, Montréal, Canada

Publisher

Informa UK Limited

Subject

Toxicology,General Medicine

Reference127 articles.

1. Successful Use of a 20% Lipid Emulsion to Resuscitate a Patient after a Presumed Bupivacaine-related Cardiac Arrest

2. AAGBI. AAGBI Safety Guideline – Management of Severe Local Anaesthetic Toxicity 2010. [cited 2015 May 20]. Available from: http://www.aagbi.org/sites/default/files/la_toxicity_2010_0.pdf.

3. ACMT Position Statement: Interim Guidance for the Use of Lipid Resuscitation Therapy

4. ASRA. Checklist for treatment of local anesthetic systemic toxicity 2011. [cited 2015 May 20]. Available from: https://www.asra.com/advisory-guidelines/article/3/checklist-for-treatment-of-local-anesthetic-systemic-toxicity.

5. Intravenous Lipid Emulsion in the Emergency Department: A Systematic Review of Recent Literature

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