Plasma paracetamol concentration at hospital presentation has a dose-dependent relationship with liver injury despite prompt treatment with intravenous acetylcysteine-Reference-Cited by-同舟云学术

Plasma paracetamol concentration at hospital presentation has a dose-dependent relationship with liver injury despite prompt treatment with intravenous acetylcysteine

Published:2016-04-25 Issue:5 Volume:54 Page:405-410
ISSN:1556-3650
Container-title:Clinical Toxicology
language:en
Short-container-title:Clinical Toxicology

Author:

Cairney David G.¹,Beckwith Hannah K. S.²,Al-Hourani Khalid¹,Eddleston Michael¹³,Bateman D. Nicholas¹,Dear James W.¹³

Affiliation:

1. NPIS Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK;

2. Department of Renal Medicine, Imperial College, London, UK;

3. Pharmacology, Toxicology and Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK

Publisher

Informa UK Limited

Subject

Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.3109/15563650.2016.1159309

Reference20 articles.

1. Acetaminophen-induced acute liver failure: Results of a United States multicenter, prospective study

2. Effect of the UK 's revised paracetamol poisoning management guidelines on admissions, adverse reactions and costs of treatment

3. Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analyses

4. Mechanistic biomarkers provide early and sensitive detection of acetaminophen‐induced acute liver injury at first presentation to hospital

5. Mechanisms of Acetaminophen-Induced Liver Necrosis

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