Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase-Reference-Cited by-同舟云学术

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Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase

Published:2010-02-23 Issue:4 Volume:25 Page:509-512
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Kuca Kamil¹²³,Musilek Kamil²³,Jun Daniel¹²,Pohanka Miroslav¹,Ghosh Kallol Kumar⁴,Hrabinova Martina¹

Affiliation:

1. Center of Advanced Studies, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic

2. Department of Toxicology, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic

3. Department of Chemistry, Faculty of Sciences, J.E. Purkinje University, Usti nad Labem, Czech Republic

4. School of Studies in Chemistry, Pt. Ravishankar Shukla University, Raipur (C.G.), India

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.3109/14756360903357569

Reference46 articles.

1. Synthesis of a potential reactivator of acetylcholinesterase—1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium)propane dibromide

2. The Development of New Structural Analogues of Oximes for the Antidotal Treatment of Poisoning by Nerve Agents and the Comparison of Their Reactivating and Therapeutic Efficacy with Currently Available Oximes

3. Oximes-induced reactivation of rat brain acetylcholinesterase inhibited by VX agent

4. (09) Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Experimental and Established Oximes as Pretreatment before Acute Exposure to Azinphos-Methyl;International Journal of Molecular Sciences;2021-03-17

2. Combined Pre- and Posttreatment of Paraoxon Exposure;Molecules;2020-03-27

3. Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness;Toxicology Letters;2020-03

4. Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators;Toxicology and Applied Pharmacology;2019-11

5. Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation;Chemico-Biological Interactions;2019-08

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