Preparation and in-vivo evaluation of dimenhydrinate buccal mucoadhesive films with enhanced bioavailability

Author:

Yildiz Pekoz Ayca1,Sedef Erdal Meryem1,Okyar Alper2,Ocak Meltem1,Tekeli Fatma3,Kaptan Engin4,Sagirli Olcay5,Araman Ahmet1

Affiliation:

1. Department of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul University, Beyazit-Istanbul, Turkey,

2. Department of Pharmacology, Faculty of Pharmacy, Istanbul University, Beyazit-Istanbul, Turkey,

3. Institute of Experimental Medicine (DETAE), Istanbul University, Capa, Istanbul, Turkey,

4. Department of Biology, Faculty of Science, Istanbul University, Vezneciler-Istanbul, Turkey, and

5. Department of Analytical Chemistry, Faculty of Pharmacy, Istanbul University, Beyazit-Istanbul, Turkey

Publisher

Informa UK Limited

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology

Reference60 articles.

1. Brunton L, Parker K, Blumenthal D, Buxton I. Goodman and Gilman’s Manually of Pharmacology and Therapeutics. New York: Mc Graw-Hill; 2008:406

2. British Pharmacopoeia. UK: 2010:703

3. Studies on controlled release dimenhydrinate from matrix tablet formulations

4. Sweetman SC. Martindale: the extra pharmacopeia. 34th edn. Suffolk: The Pharmaceutical Press; 2005:431

5. Characterization of polymeric dispersions of dimenhydrinate in ethyl cellulose for controlled release

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