Cloning of Bovine Eukaryotic Translation Initiation Factor 4E (eIF-4E) and Its Expression in the Bovine Mammary Gland at Different Physiological Stages
Author:
Publisher
Informa UK Limited
Subject
Endocrinology,Genetics,Molecular Biology,Biochemistry
Link
http://www.tandfonline.com/doi/pdf/10.3109/10425170109084455
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1. Overexpression of the proto-oncogene/translation factor 4E in breast-carcinoma cell lines
2. Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology.
3. Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F.
4. Insulin and Phorbol Ester Stimulate Initiation Factor eIF-4E Phosphorylation by Distinct Pathways in Chinese Hamster Ovary Cells Overexpressing the Insulin Receptor
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