TDP-43 and ubiquitinated cytoplasmic aggregates in sporadic ALS are low frequency and widely distributed in the lower motor neuron columns independent of disease spread
Author:
Publisher
Informa UK Limited
Subject
Clinical Neurology,Neurology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.3109/17482961003602363
Reference18 articles.
1. Ubiquitin deposits in anterior horn cells in motor neurone disease
2. Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
3. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
4. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis withSOD1 mutations
5. Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS
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