Preemptive leucovorin administration minimizes pralatrexate toxicity without sacrificing efficacy
Author:
Affiliation:
1. Department of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Publisher
Informa UK Limited
Subject
Cancer Research,Oncology,Hematology
Link
https://www.tandfonline.com/doi/pdf/10.3109/10428194.2013.779688
Reference12 articles.
1. Phase II-I-II Study of Two Different Doses and Schedules of Pralatrexate, a High-Affinity Substrate for the Reduced Folate Carrier, in Patients With Relapsed or Refractory Lymphoma Reveals Marked Activity in T-Cell Malignancies
2. Pralatrexate: basic understanding and clinical development
3. Pralatrexate in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma: Results From the Pivotal PROPEL Study
4. Identification of an active, well-tolerated dose of pralatrexate in patients with relapsed or refractory cutaneous T-cell lymphoma
5. Single agent and combination studies of pralatrexate and molecular correlates of sensitivity
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