Results of Transrectal Ultrasound-Guided Prostate Biopsy by the Method of 12 Cores at Can Tho University Hospital

Abstract

Background: Prostate cancer is a common disease in men, with the second-highest incidence rate and the fifth-highest mortality rate worldwide. Diagnoses to determine prostate cancer need to be based on factors such as rectal examination, total PSA in serum, and the result of a prostate biopsy. Our study aimed to evaluate the results of rectal prostate biopsies of 12 cores under the direction of ultrasound. Objectives: Assess results of transrectal ultrasound-guided prostate biopsy by the method of 12 cores. Methods: This was cross-sectional research of 60 patients with prostate tumors with indications for biopsy from 5/2021 to 5/2022 at the Can Tho University of Medicine and Pharmacy Hospital. Our research conducts medical history and patient history to score 2 points on IPSS (International Prostate Syndrome Score) and QoL (Quality of Life Index), and we use the descriptive statistic method to analyze data. The indications for the prostate biopsy were abnormal digital rectal examination findings and/or an elevated serum total prostate-specific antigen (PSA) level (greater than 10 ng/mL). The participants received prophylactic vein bacsulfo (1000 mg) and oral metronidazol (500 mg) before and maintained continued after about 3 days. A Fleet enema was self-administered the night before the procedure for rectal cleansing. Results: The average age of patients was 68.72, and the most common reason for hospitalization was dysuria at 80%. The average IPSS was 26.21 ± 4.49, the average QoL was 3.38 ± 0.67, and the average total PSA was 26.11 ng/mL. The prostate cancer detection rate after the biopsy was 40% (24/60). Gleason’s scores determined accounted for 45.83% (11/24) from 8 points or more. There were two cases of strong rectal bleeding (3.33%) and one case of strong hematuria (1.67%). Conclusions: Transrectal ultrasound-guided prostate biopsy is valuable in the diagnosis of prostate cancer and feasible at our hospital.