The Outcome of Left Ventricular Thrombosis in Patients with Coronavirus Disease 2019 Infection

Abstract

Background: Left ventricular thrombus (LVT) is a significant cardiovascular complication in patients with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Objectives: This study aimed to investigate the risk factors and outcomes of COVID-19 patients with LVT. Methods: Twenty-two COVID-19 patients with normal myocardial signals on echocardiography, normal coronary findings, and normal cardiac biochemical tests but with LVT were included. Patients were aged between 18 and 65 years. Data on risk factors and outcomes were collected from electronic records, including patient demographics, clinical characteristics, comorbidities, laboratory values, and in-hospital outcomes. Results: Of the 22 patients surveyed, 9 (40.8%) were admitted to the ICU, and 4 (18.1%) died during follow-up. Mechanical ventilation was required for 6 (27.2%) patients. Acute respiratory distress syndrome (ARDS) and acute kidney injury were reported in 6 and 5 patients, respectively. Shock was experienced by 27% of patients (6 individuals), and ventricular arrhythmias were reported in only one patient. Conclusions: In summary, COVID-19 patients who developed LVT during hospitalization had a higher mortality rate. Screening echocardiography at admission may benefit such patients.