Abstract
Background: Premature ejaculation (PE) is a sexual disorder in men with significant prevalence among neurology patients. Epilepsy is one such condition where the prevalence of PE has been notably high. Objectives: This study aimed to compare the prevalence of PE in men with focal epilepsy and generalized tonic-clonic seizures (GTCS). Methods: In this cross-sectional observational study, 200 patients with epilepsy were included, with 100 patients having focal epilepsy and 100 patients having GTCS. The study utilized the demographic profile form, Men’s Sexual Health Questionnaire (MSHQ), Sexual Quality of Life-Men (SQOL-M), and premature ejaculation diagnostic tool (PEDT). Patients who visited specialized clinics and hospitals and met the inclusion criteria were recruited. Data were then analyzed using SPSS statistical software. Results: The results showed that the mean (SD) age of patients in the focal epilepsy group was 30.18 (3.85). The mean (SD) scores for the MSHQ, SQOL-M, and PEDT tools were 51.81 (11.98), 34.75 (9.36), and 8.63 (4.79), respectively. Although the mean (SD) PE score in the focal epilepsy group was 9.17 (4.49), higher than that of the GTCS group at 8.09 (5.04), the difference was not statistically significant. Additionally, there was a significant relationship between the PEDT score, SQOL-M score, and MSHQ score (P < 0.05). The MSHQ and SQOL-M scores were lower in patients with PE disorder. Conclusions: Sexual disorders, including PE, are significantly prevalent in both groups of patients with epilepsy. Therefore, it is essential to implement both pharmacological and non-pharmacological interventions to reduce the incidence of PE in these patients.