Abstract
Background: Sarcopenia is the age-related progressive loss of muscle mass and strength. The main symptom of the condition is muscle weakness. Objectives: The aim of the present study was to determine the effect of 12 weeks of Nordic walking on the expression of the cardiovascular biomarker galectin 3 gene and some new metabolic markers in elderly men with osteosarcopenic obesity. Methods: Twenty elderly men with a Mean age of 60 to 80 years, who had osteosarcopenic obesity with a body mass index (equal to and above 30) and body fat percentage (equal to and above 30) participated in this research and they were randomly divided into 2 Nordic walking training groups and a control group (10 people in each group). The Nordic walking training program was implemented for 12 weeks and 3 days a week. The intensity of the exercises in each session was 50 to 75% of the maximum heart rate and the duration of each exercise session was 60 minutes. Results: 12 weeks of Nordic walking exercises caused a significant decrease in the circulating levels of galectin-3 (P = 0.001) and a decrease in the TyG-BMI index (P = 0.001) in the subjects. But there was no significant effect on the atherogenic index of plasma (AIP) (P = 0.265) and TyG (P = 0.126) and TyG-BMI (P = 0.347) indices of the subjects. Conclusions: Nordic walking exercise plays an important role in reducing cardiovascular risks by reducing galectin 3 biomarker and atherogenic plasma index (AIP).