Abstract
Background: Dyspepsia is a common disorder that puts much socio-economic pressure on patients due to its high prevalence. Various factors can cause this disorder. Objectives: This study investigated the relationship between dyspepsia, quality of life, and personality traits. Methods: This case-control study selected 50 people with dyspepsia and 50 healthy people by simple random method. Patients' demographic information was recorded using a researcher-made checklist. Then, the WHOQOL-BREF questionnaire measured the quality of life, and the NEO-FFI-60 questionnaire assessed personality traits. Finally, the data were analyzed using a chi-square test, independent t-test, and multivariate linear and logistic regression by SPSS software version 22 at the significance level of 0.05. Results: The mean score of anger was higher in people with dyspepsia than in healthy people (P = 0.000), but other indicators were higher in healthy people than in people with dyspepsia (P < 0.05). Finally, the personality traits of anger, acceptance of new experiences, and conscientiousness had a significant relationship with quality of life in people with dyspepsia (P < 0.05). Conclusions: Dyspepsia reduces the quality of life and affects the personality traits of individuals. Thus, improving dyspepsia can improve patients' personality traits and quality of life.