Resting-State Electroencephalographic Coherence in Recently Abstinent Methamphetamine Users

Author:

Shafiee-Kandjani Ali RezaORCID,Jahan Ali,Moghadam-Salimi Maryam,Fakhari Ali,Nazari Mohammad Ali,Sadeghpour Sona

Abstract

Background: Long-term use of Methamphetamine (MA) can impose some deficits by its toxicity on the brain structure and function. It can also alter brain electrical activity and cortico-cortical neural connections. The coherence index of electroencephalography reflects the temporal integration of electrical oscillations between different sites of the brain and could be affected by the chronic use of MA. Objectives: In this study, we aimed to compare quantitative electroencephalography (QEEG) coherence as an index of brain connectivity between methamphetamine users and healthy people. Materials and Methods: In this descriptive-analytical study, 18 patients with methamphetamine abstinence and 18 healthy people with no history of psychiatric illness were evaluated. Electroencephalography was recorded during eyes-open and eyes-closed states for each group, and then, the analysis for coherence between different twin electrodes was performed. The evaluation was done on occipital, temporal, frontal, and parietal lobes. Repeated-measures ANOVA and t-test were conducted for statistical analysis (P < 0.05). Results: Coherence differences in frontal, temporal, and occipital lobes were not significant while coherence was significantly different in parietal lobes between the groups (P = 0.03), so that a decrease in C3-CZ electrode coherence in both delta and theta bands in methamphetamine users was significant (P = 0.03 and P = 0.01, respectively). Conclusions: It was revealed that brain coherence could be changed after the chronic use of MA, especially in slow waves. This could be an indicator of structural and functional damage in the neuronal population and show less regional integration in cortical areas in MA users, possibly due to substance toxicity.

Publisher

Briefland

Subject

Psychiatry and Mental health,Clinical Psychology,Medicine (miscellaneous)

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3