Effect of Magnesium Sulfate Addition to Intrathecal Marcaine on Pain Management After Cesarean Section

Abstract

Background: The cesarean section plays an important role in reducing mortality rates and postpartum complications in the mother and fetus in certain deliveries. Objectives: The aim of this study was to determine the effect of magnesium sulfate supplementation on intrathecal marcain on pain control after cesarean section. Methods: This randomized clinical trial study was performed on 42 women candidates for cesarean section in Vali-e-Asr Hospital in Birjand in 2018. In each group, vital signs and pain score were assessed every 15 minutes using the Visual Intensity Pain Scale (VAS) 1,2,3,4,8,12 hours after surgery. Data were collected and analyzed using the Friedman test, t-test for independent groups, Mann-Whitney, and chi-square by SPSS software. Results: The mean age of women candidates for cesarean section was 29.11 ± 5.42 years. The mean VAS score in both groups at different times was statistically significant. At 1 and two hours after surgery, the mean VAS score in magnesium sulfate and marcaine groups was significantly higher than marcaine group and in three hours after the surgery, it was significantly less than the Marcain group but there was no significant difference in other times. Changes in pain intensity in the magnesium sulfate and marcaine groups were significantly greater than the marcaine group. Conclusions: Addition of magnesium sulfate to intrathecal marcaine has a significant effect on pain management after cesarean section.