Elimination of Helicobacter pylori Infection in Patients with Gastrointestinal Problems After Administration of Four-Drug Regimen: A Brief Report

Abstract

Background: There are a variety of treatment regimens containing several antimicrobial compounds to treat Helicobacter pylori infection. Objectives: The aim of this study was to eradicate H. pylori infection in patients with gastrointestinal problems after the administration of a four-drug regimen. Methods: This study was performed among 100 patients with gastrointestinal problems visiting Imam Khomeini Hospital in Urmia, Iran. The data were collected using a checklist that included patient information and analyzed by chi-square and t-test. Results: Out of the 100 patients visiting the clinic, 60 (60%) were male, and the rest were women. Also, 67% of the patients had pain type dyspepsia, and 33% of them postprandial distress type. In pathologic study, 38% of the patients had H. pylori infection, with a significantly higher incidence in patients with pain type dyspepsia. Conclusions: The results showed a relationship between the type of indigestion and the improvement of symptoms after receiving a four-drug regimen, indicating the need for proper planning to diagnose and treat the type of indigestion.