Comparative Analysis of Serum and Saliva Iron, Ferritin, and TIBC in Women with Iron Deficiency Anemia: Highlighting Saliva's Screening Potential

Author:

Farrokhnia TaranehORCID,Shoorgashti ReyhanehORCID,Sadeghian Mohammadreza,Hasanzade Shahab,Lesan SiminORCID,Hedayati Mahdi

Abstract

Background: Iron deficiency anemia is a prevalent form of anemia, particularly among women. Diagnosing and tracking this condition typically requires various measurements of serum iron, ferritin, and total iron-binding capacity (TIBC) through blood testing. Objectives: This study aims to evaluate the utility of saliva as a predictive marker for monitoring iron levels in iron deficiency anemia by comparing and correlating iron, ferritin, and TIBC levels in the serum and saliva of anemic and healthy women. Methods: In this comparative analysis, 40 women aged 20 - 40 with a similar periodontal status (anemic subjects = 20 and healthy subjects = 20) were examined. After a complete hematological and oral examination, salivary samples were collected using the spitting method, and iron, ferritin, and TIBC levels were measured and compared to the serum levels. Data were analyzed using SPSS 24. Results: The study results showed that the differences in saliva iron and ferritin levels were insignificant between the two groups (P-value = 0.07 and 0.26, respectively), but those were statistically significant in the serum (P-value = 0.0001 and 0.0001, respectively). Additionally, a significant difference was found in the saliva TIBC level (P-value = 0.001), which was negligible in the serum (P-value = 0.118). Conclusions: The results underscore the efficacy of integrating both serum and saliva analyses for comprehending iron-related parameters. While saliva analysis cannot entirely substitute for serum analysis, it represents a convenient approach that may serve as an initial step or be employed in large-scale anemia screenings.

Publisher

Briefland

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3