Vaccinal prevention of Tick-Borne Encephalitis in chelyabinsk Region: Dynamics of Vaccination, population Immunity, Analysis of TBE cases in Vaccinated persons

Author:

Luchinina S. V.,Semenov A. I.,Stepanova O. N.,Pogodina V. V.,Gerasimov S. G.,Shcherbinina M. S.,Kolesnikova L. I.,Suslova T. A.

Abstract

The Chelyabinsk Region (Southern Urals) is high endemic territory. The TBE incidence is 3.57 ± 1.7 per 100 000 of population. A level of vaccination against TBE increased from 0.3 to 34.8% in 1999 - 2013. Specific immunity of population in 35.9% is connected with vaccination, in 64.1% with natural immunity consequently latent contact with TBE virus. Dynamics of vaccinal prevention, increasing of population immunity in different landscapes, and in different age groups were studied. 77.7% of TBE patients did not vaccinated, 18.2% received of specific immunoglobulin at postexposition and 3.7% persons were vaccinated. Unusual lethal case in patient, who received 8 doses of vaccine is analysed in this article.

Publisher

LLC Numicom

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,Epidemiology

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