Достижения в элиминации кори и краснухи в Республике Беларусь

Abstract

The analysis of measles and rubella surveillance data in Belarus for 2012 - 2015 was presented. Laboratory diagnosis based on revealing of specific IgM antibodies, dynamic of IgG concentration or detection of viral RNA. Virus genotyping was done by sequence analysis of C-terminal region of N gene (for measles) and fragment of E1 gene (for rubella). Among 1470 suspected measles/rubella cases 92 measles cases (10 - in 2012, 16 - in 2013, 64 - in 2014, 2 - in 2015) and 13 rubella cases (10 - in 2012, in 1 - in 2013, 2014 and 2015) were confirmed. The vast majority of measles patients (88.3%) and all rubella patients were older 20 years of age. Within 4 years of observation 6 chains of measles virus transmission were revealed (2 chains in 2012, 2013 and 2014 each), for each of them genotype of virus was determined. There were also 19 single cases of measles without spreading and virus genotype was determined for 17 of them. On the basis of epidemiological data and molecular investigations 14 measles cases were classified as imported (from Russia (6), Ukraine (2), Thailand (2), Egypt, Malaysia, the United Arab Emirates, Italy), 78 - related to imported. All 13 rubella cases were represented by single cases, 4 of them were imported (from China (2), Thailand, Poland), 9 - related to imported. The absence of endemic circulation of both measles and rubella viruses in the Republic of Belarus was demonstrated and confirmed by the European Regional Commission for verification of measles and rubella elimination.