Preventing Complications in Pregnant Women with Mild and Moderate Severity of Acute Respiratory Infections

Author:

Kostinov M. P.,Lukachev I. V.,Meshcheryakova A. K.,Magarshak O. O.,Polischuk V. B.,Faizuloev E. B.,Guseva T. S.,Parshina O. V.,Novikova S. V.,Ignatieva M. A.,Savisko A. A.,Brico N. I.

Abstract

Relevance.Pregnant women are often exposed to respiratory viruses. Occasionally, the fetus may be harmed by the virus.Goalto present materials revealing the safety and effectiveness of local interferon therapy used in the initial stage of acute respiratory infection in pregnant women from 14 weeks of gestation.Materials and methods.An in-depth analysis of the results of a study of the safety and efficacy of local interferon-therapy of respiratory infections presented in more than 60 literature sources, and own research.Results.It is shown that the inclusion of interferon-α2b (Viferon®) preparation in the complex of basic ARI therapy in pregnant women leads to a decrease in the content in the nasal washout of IL-8, the growth of T-lymphocytes and T-helpers, a more pronounced tendency to decrease natural killers; positively affects the microbiocenosis of the mucous membranes of the upper respiratory tract; leads to a reduction in symptoms of acute pharyngitis, bacterial complications from the upper respiratory tract and, as a consequence, minimizes the need for systemic antibacterial therapy.Conclusions.The conclusion is made about the expediency of including the recombinant interferon-α2b (Viferon®) preparation in intranasal gel form in the complex of basic ARI therapy in pregnant women. 

Publisher

LLC Numicom

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,Epidemiology

Reference61 articles.

1. Bocharova I. I., Kostinov M. P., Novikova S. V., Shmit’ko A. D, Obidina A. A., Tsivtsivadze E. B. Transplacental antibodies to measles virus in newborns in different pregnancy in their mothers. Rossiyskiy vestnik akushera-ginekologa. [Russian Bulletin of Obstetrician-Gynecologist]. 2014; 2 (14): 14–18.

2. Shmit’ko A. D., Novikova S. V., Bocharova I. I., Yakubina A. A., Kostinov M. P. et al. Mechanisms and factors affecting the transplacental transmission of IgG antibodies in the mother-placenta-fetus system. Rossiyskiy vestnik akushera-ginekologa. [Russian Bulletin of Obstetrician-Gynecologist]. 2014; 6 (14): 27–31.

3. Kostinov M. P., Cherdantsev A. P., Semenova S. S., Tarbaeva D. A., Savis’ko A. A., Serova O. F. et al. Obstetric and perinatal outcomes after vaccination against influenza or respiratory infection. Ginegologiya. [Gynecology]. 2015; 3 (14): 43–46.

4. Zaitsev A. A., Gorelov A. V., Klochkov O. I. Acute respiratory viral infections: perspectives of antiviral therapy. Vestnik semeinoi medicini. [Herald of Family Medicine]. 2009; 5: 18–23.

5. Sinopalnikov A. I. The Common Cold. Community-acquired infections of the respiratory tract. Moscow. Premier MT-Our City; 2007: 131–144.

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