Severe COVID-19 and Retina: Are There Any Retinal Manifestations?

Author:

Gündogan Medine1,Kiliç Soner2,Göktas Sertan1,Vural Esra1,Sirem Muhammed Rasit1,Ünal Sefa1,Celik Ilhami3

Affiliation:

1. Ophthalmology, Kayseri City Education and Research Hospital, Kayseri, Turkey

2. Neurology, Kayseri City Education and Research Hospital, Kayseri, Turkey

3. Infectious Diseases and Clinical Microbiology, Kayseri City Education and Research Hospital, Kayseri, Turkey

Abstract

Abstract Purpose To investigate whether there are retinal lesions associated with severe COVID-19. Methods We studied 232 symptomatic subjects aged 18 – 65 years who had severe COVID-19 and had received treatment. The evaluations included ophthalmological examinations, optical coherence tomography (OCT), imaging modalities with near infrared reflectance (NIR), fundus autofluorescence (FAF), and fundus photography (FP). Results The mean age of the patients was 49 years, and 67.6% of them were men. There were no findings of microhemorrhage, cotton wool spots (CWS), vitritis, or retinitis in the examination and imaging. Conclusions This study indicates that retinal involvement as a complication associated with COVID-19 is questionable, although some reports have demonstrated a relationship that may occur secondary to existing systemic diseases.

Publisher

Georg Thieme Verlag KG

Subject

Ophthalmology

Reference20 articles.

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3. The role of apoptosis within the retina of coronavirus-infected mice;Y Wang;Invest Ophthalmol Vis Sci,2000

4. Detection of SARS-CoV-2 in human retinal biopsies of deceased COVID-19 patients;M Casagrande;Ocul Immunol Inflamm,2020

5. Angiotensin II and its receptor subtypes in the human retina;P Senanayake;Invest Ophthalmol Vis Sci,2007

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