Photon-counting computed tomography – clinical application in oncological, cardiovascular, and pediatric radiology

Author:

Hagen Florian1ORCID,Soschynski Martin2,Weis Meike3,Hagar Muhammad Taha2,Krumm Patrick1,Ayx Isabelle3,Taron Jana2,Krauss Tobias2,Hein Manuel4,Ruile Philipp4,von zur Muehlen Constantin4,Schlett Christopher L.2,Neubauer Jakob2ORCID,Tsiflikas Ilias1,Russe Maximilian Frederik2,Arnold Philipp2,Faby Sebastian5ORCID,Froelich Matthias F.3ORCID,Weiß Jakob2,Stein Thomas2,Overhoff Daniel3ORCID,Bongers Malte1ORCID,Nikolaou Konstantin1,Schönberg Stefan O.3,Bamberg Fabian2,Horger Marius1

Affiliation:

1. Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany

2. Department of Diagnostic and Interventional Radiology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

3. Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

4. Department of Cardiology & Angiology, University Heart Center Freiburg – Bad Krozingen, University Hospital Freiburg, Faculty of medicine, 79106 Freiburg, Germany

5. Computed Tomography, Siemens Healthcare GmbH, Forchheim, Germany

Abstract

Background Photon-counting detector computed tomography (PCD-CT) is a promising new technology with the potential to fundamentally change workflows in the daily routine and provide new quantitative imaging information to improve clinical decision-making and patient management. Method The contents of this review are based on an unrestricted literature search of PubMed and Google Scholar using the search terms “photon-counting CT”, “photon-counting detector”, “spectral CT”, “computed tomography” as well as on the authors’ own experience. Results The fundamental difference with respect to the currently established energy-integrating CT detectors is that PCD-CT allows for the counting of every single photon at the detector level. Based on the identified literature, PCD-CT phantom measurements and initial clinical studies have demonstrated that the new technology allows for improved spatial resolution, reduced image noise, and new possibilities for advanced quantitative image postprocessing. Conclusion For clinical practice, the potential benefits include fewer beam hardening artifacts, a radiation dose reduction, and the use of new or combinations of contrast agents. In particular, critical patient groups such as oncological, cardiovascular, lung, and head & neck as well as pediatric patient collectives benefit from the clinical advantages. Key Points:  Citation Format

Funder

Ministerium für Wirtschaft, Arbeit und Tourismus, Baden Württemberg

Publisher

Georg Thieme Verlag KG

Subject

Radiology, Nuclear Medicine and imaging

Reference81 articles.

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