Chemosaturation of the Liver – an Update-Reference-Cited by-同舟云学术

Chemosaturation of the Liver – an Update

Published:2022-08-17 Issue:01 Volume:195 Page:30-37
ISSN:1438-9029
Container-title:RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
language:de
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Author:

Ebel Sebastian¹^ORCID,Struck Manuel Florian²^ORCID,van Boemmel Florian³,Beeskow Anne Bettina¹,Gößmann Holger¹,Denecke Timm¹

Affiliation:

1. Klinik und Poliklinik für diagnostische und interventionelle Radiologie, Leipzig University, Leipzig, Germany

2. Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Leipzig University, Leipzig, Germany

3. Klinik für Innere Medizin II, Sektion für Hepatologie, Leipzig University, Leipzig, Germany

Abstract

Background Percutaneous hepatic perfusion (CS-PHP) is a treatment option for primary and secondary liver neoplasms and subject of intensive research. This present article provides an overview of CS-PHP regarding patient safety, feasibility and effectiveness based on recent studies. Method We performed a PubMed search including the search terms chemosaturation, hepatic chemosaturation, percutaneous perfusion and melphalan. Results and conclusion CS-PHP is a promising procedure for the treatment of uveal melanoma and cholangiocellular carcinoma. There are insufficient data regarding the effectiveness of CS-PHP with respect to other tumor entities. Since CS-PHP can be accompanied by multiple transient side effects and complications, close interdisciplinary cooperation is necessary. Key Points: Citation Format

Publisher

Georg Thieme Verlag KG

Subject

Radiology, Nuclear Medicine and imaging

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1858-3418.pdf

Reference40 articles.

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3. Percutaneous isolated hepatic perfusion (chemosaturation) with melphalan following right hemihepatectomy in patients with cholangiocarcinoma and metastatic uveal melanoma: peri- and post-interventional adverse events and therapy response compared to a matched group without prior liver surgery;C LA Dewald;Clin Exp Metastasis,2020

4. Percutaneous hepatic melphalan perfusion: Single center experience of procedural characteristics, hemodynamic response, complications, and postoperative recovery;M F Struck;PLoS One,2021

5. Prospective Clinical and Pharmacological Evaluation of the Delcath System’s Second-Generation (GEN2) Hemofiltration System in Patients Undergoing Percutaneous Hepatic Perfusion with Melphalan;E M de Leede;Cardiovasc Intervent Radiol,2017