Dual Responses of Fluorescence and Circular Dichroism for Antibiotics by a Cationic Cage in Water

Author:

Dong Yunhong1,Cheng Lin1,Cao Liping1,Duan Yanjuan1,Xu Huiru2,Dong Ruonan2,Guo Baolin2

Affiliation:

1. Xi’an Key Laboratory of Functional Supramolecular Structure and Materials, College of Chemistry and Materials Science, Northwest University

2. State Key Laboratory for Mechanical Behavior of Materials, and Frontier Institute of Science and Technology, Xi’an Jiaotong University

Abstract

AbstractA tetraphenylethene (TPE)-based cationic cage (1) can form a 1:2 host–guest complex with antibiotics in water and imparts dual responses of fluorescence and circular dichroism (CD) to antibiotics based on the fluorescence and adaptive chiral conformation of the TPE units. Moreover, the host–guest complexes 1⊃(antibiotic)2 exhibited good antibacterial activity.

Funder

Natural Science Basic Research Program of Shaanxi Province

Fok Ying Tong Education Foundation

National Natural Science Foundation of China

Xi'an Key Laboratory of Functional Supramolecular Structure and Materials

Shaanxi Fundamental Science Research Project for Chemistry and Biology

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

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