Affiliation:
1. School of Pharmacy and Food Engineering, Wuyi University
2. School of Pharmaceutical Sciences, Sun Yat-sen University
Abstract
AbstractFluorinated molecules are widely used in pharmaceutical and agrochemical industries. Multifluoroalkyl-containing compounds have attracted increasing attention for their unique ability to alter the activity of drugs and bioactive molecules. Herein, we report an efficient Rh(III)-catalyzed, redox-neutral, C–H multifluoroalkenylation of benzamides with multifluoroalkenes, which provides a versatile protocol for accessing a wide range of multifluoroalkenylated arenes.
Funder
Basic and Applied Basic Research Foundation of Guangdong Province
Wuyi University