A New Approach to the Synthesis of the Nonpeptide NOP Receptor Antagonist J-113397
Author:
Publisher
Georg Thieme Verlag KG
Subject
Organic Chemistry,Catalysis
Link
http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-966037
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Access to N-Thioalkenyl and N-(o-Thio)aryl-benzimidazol-2-ones by Ring Opening of Thiazolobenzimidazolium and Benzimidazobenzothiazolium Salts and C–O Bond Cleavage of an Alkoxide;The Journal of Organic Chemistry;2015-03-11
2. Nitrile Oxide versus Nitrone - Switching Regioselectivity of Intramolecular 1,3-Dipolar Cycloadditions towards the Preparation of Aminopiperidinecarboxylates;European Journal of Organic Chemistry;2013-09-20
3. Efficient and practical asymmetric synthesis of 1-tert-butyl 3-methyl (3R,4R)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1,3-dicarboxylate, a useful intermediate for the synthesis of nociceptin antagonists;Tetrahedron: Asymmetry;2009-11
4. Improved Synthesis of the ORL Antagonist 1-[(3R,4R)-1-Cyclooctylmethyl-3-ethoxycarbonyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397);Synthetic Communications;2008-05-23
5. A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay;Bioorganic & Medicinal Chemistry;2008-01
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