Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer-Reference-Cited by-同舟云学术

Update Breast Cancer 2022 Part 5 – Early Stage Breast Cancer

Published:2023-03 Issue:03 Volume:83 Page:289-298
ISSN:0016-5751
Container-title:Geburtshilfe und Frauenheilkunde
language:de
Short-container-title:Geburtshilfe Frauenheilkd

Author:

Fehm Tanja N.¹,Welslau Manfred²,Müller Volkmar³,Lüftner Diana⁴,Schütz Florian⁵,Fasching Peter A.⁶,Janni Wolfgang⁷,Thomssen Christoph⁸,Witzel Isabell³,Beierlein Milena⁶,Belleville Erik⁹,Untch Michael¹⁰,Thill Marc¹¹,Tesch Hans¹²,Ditsch Nina¹³,Lux Michael P.¹⁴,Aktas Bahriye¹⁵,Banys-Paluchowski Maggie¹⁶,Kolberg-Liedtke Cornelia¹⁷,Hartkopf Andreas D.⁷,Wöckel Achim¹⁸,Kolberg Hans-Christian¹⁹,Harbeck Nadia²⁰,Stickeler Elmar²¹

Affiliation:

1. Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Düsseldorf, Germany

2. Onkologie Aschaffenburg, Aschaffenburg, Germany

3. Department of Gynecology, Hamburg-Eppendorf University Medical Center, Hamburg, Germany

4. Immanuel Hospital Märkische Schweiz, Buckow; Medical University of Brandenburg Theodor-Fontane, Brandenburg, Germany

5. Gynäkologie und Geburtshilfe, Diakonissen-Stiftungs-Krankenhaus Speyer, Speyer, Germany

6. Erlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany

7. Department of Gynecology and Obstetrics, Ulm University Hospital, Ulm, Germany

8. Department of Gynaecology, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany

9. ClinSol GmbH & Co. KG, Würzburg, Germany

10. Clinic for Gynecology and Obstetrics, Breast Cancer Center, Gynecologic Oncology Center, Helios Klinikum Berlin Buch, Berlin, Germany

11. Agaplesion Markus Krankenhaus, Department of Gynecology and Gynecological Oncology, Frankfurt, Germany

12. Oncology Practice at Bethanien Hospital, Frankfurt am Main, Germany

13. Department of Gynecology and Obstetrics, University Hospital Augsburg, Augsburg, Germany

14. Klinik für Gynäkologie und Geburtshilfe, Frauenklinik St. Louise, Paderborn, St. Josefs-Krankenhaus, Salzkotten, St. Vincenz Krankenhaus GmbH, Paderborn, Germany

15. Department of Gynecology, University of Leipzig Medical Center, Leipzig, Germany

16. Department of Gynecology and Obstetrics, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany

17. Department of Gynecology and Obstetrics, University Hospital Essen, Essen, Germany

18. Department of Gynecology and Obstetrics, University Hospital Würzburg, Würzburg, Germany

19. Department of Gynecology and Obstetrics, Marienhospital Bottrop, Bottrop, Germany

20. Breast Center, Department of Gynecology and Obstetrics and CCC Munich LMU, LMU University Hospital, Munich, Germany

21. Department of Obstetrics and Gynecology, Center for Integrated Oncology (CIO Aachen, Bonn, Cologne, Düsseldorf), University Hospital of RWTH Aachen, Aachen, Germany

Abstract

AbstractThe treatment of patients with early stage breast cancer has changed in recent years due to the introduction of pembrolizumab, olaparib, and abemaciclib. These and other drugs with the same class of active ingredient are currently in trial for various indications. This review article summarizes the latest results that have either been presented at major conferences such as the ESMO 2022 or published recently in international journals. This includes reports on newly discovered breast cancer genes, atezolizumab in neoadjuvant therapy in HER2-positive patients, long-term data from the APHINITY study, and on how preoperative peritumoral application of local anesthetics can influence the prognosis. We also present solid data on dynamic Ki-67 from the ADAPT studies.

Publisher

Georg Thieme Verlag KG

Subject

Maternity and Midwifery,Obstetrics and Gynecology

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-2018-9053.pdf

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