Novel LC-MS/MS Method for Simultaneous Quantification of KW-7158, a New Drug Candidate for Urinary Incontinence and Bladder Hyperactivity, and its Metabolites in Rat Plasma: A Pharmacokinetic Study in Male and Female Rats

Author:

Maeda H.123,Fujita K.2,Kobayashi H.2,Ushiki J.2,Nakanishi T.3,Tamai I.3

Affiliation:

1. Clinical Science Department, Development Division, Kyowa Hakko Kirin Co., Ltd., Tokyo, Japan

2. Pharmacokinetic Research Laboratories, Research Division, Kyowa Hakko Kirin Co., Ltd., Tokyo, Japan

3. Department of Membrane Transport and Biopharmaceutics, Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa, Japan

Publisher

Georg Thieme Verlag KG

Subject

Drug Discovery

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Thiepanes and Thiepines;Comprehensive Heterocyclic Chemistry IV;2022

2. K+ Channels in Primary Afferents and Their Role in Nerve Injury-Induced Pain;Frontiers in Cellular Neuroscience;2020-09-17

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