A Convenient One-pot Synthesis of Chromenyl Acrylates and Acrylonitriles

Author:

Proença Fernanda1,Lopes Diogo1,Costa Marta23,Louçano João1

Affiliation:

1. Department of Chemistry, University of Minho

2. Life and Health Sciences Research Institute (ICVS), University of Minho

3. ICVS/3B’s – PT Government Associate Laboratory

Abstract

2H-Oxo-chromenyl acrylates and 2H-imino-chromenyl acrylonitriles have been prepared from a salicylaldehyde and ethyl cyanoacetate or 2-amino-1,1,3-tricyanopropene, respectively. The reaction occurs in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) and the products were isolated in good to quantitative yields. Despite the simplicity of the synthesis, this is the first time that these substituted chromenes have been isolated.

Funder

Fundação para a Ciência e a Tecnologia

Federación Española de Enfermedades Raras

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. New Heterocyclization Reactions with Malononitrile Dimer;Russian Journal of General Chemistry;2024-05

2. Reactions of Aldehydes and Ketones and Their Derivatives;Organic Reaction Mechanisms Series;2024-03-15

3. Six-membered ring systems: with O and/or S atoms;Progress in Heterocyclic Chemistry;2021

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