Affiliation:
1. Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University
Abstract
In the selective N-arylation of amines or azoles with aryl halides, methyl-α-d-glucopyranoside (MG) was found to function as a green ligand of copper powder. In addition, nitrogen heterocyclic amine compounds can also undergo the N-arylation coupling with heterocyclic aryl chlorides. This process allows access to a variety of aromatic amines and aryl azoles under mild reaction conditions, has good tolerance, and proceeds in moderate to high yield.
Funder
Natural Science Foundation of Liaoning Province
Subject
Organic Chemistry,Catalysis
Cited by
6 articles.
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